human APLP1 Over-expression AAV

Name
AAV-h-APLP1

Cat No
AAV-201158

Availability
4-5 weeks

This is an AAV expressing Human APLP1.

AAV-201158

AAV-h-APLP1

Ready-to-use AAV expressing Human APLP1 (amyloid beta precursor like protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

APLP

Description (Vector)

APLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene ID

333

Gene Name (Vector)

amyloid beta precursor like protein 1

Gene Symbol

APLP1

HGNC ID

HGNC:597

ORF Size (aa)

1953

ORF Size (bp)

1953 bp

RefSeq ID

NM_005166

RefSeq Synonyms

NM_005166, NM_001024807, BC012889,

Species

human

UniGene ID

Hs.74565

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.