human APLP1 Over-expression AAV

Name 
AAV-h-APLP1
Cat No 
AAV-201158
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human APLP1.

AAV-201158
AAV-h-APLP1

Ready-to-use AAV expressing Human APLP1 (amyloid beta precursor like protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
APLP
Description (Vector)
APLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
333
Gene Name (Vector)
amyloid beta precursor like protein 1
Gene Symbol
APLP1
HGNC ID
HGNC:597
ORF Size (aa)
1953
ORF Size (bp)
1953 bp
RefSeq ID
NM_005166
RefSeq Synonyms
NM_005166, NM_001024807, BC012889,
Species
human
UniGene ID
Hs.74565

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.