human SMG6 Adenovirus

Name 
Ad-h-SMG6
Cat No 
ADV-223754
Availability
4-5 weeks

This is an Adenovirus expressing Human SMG6.

ADV-223754
Ad-h-SMG6

Ready-to-use Adenovirus expressing Human SMG6 (smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C17orf31; EST1A; KIAA0732; SMG-6;
Description (Vector)
SMG6 encodes a protein which is part of the telomerase ribonucleoprotein complex and binds single-stranded DNA found at the telomeres, but the product of this gene also participates in the nonsense-mediated mRNA decay (NMD) pathway. The encoded protein contains two binding sites for components of the exon junction complex (EJC); interaction between the encoded protein and the EJC is necessary for NMD activity. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
23293
Gene Name (Vector)
smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)
Gene Symbol
SMG6
HGNC ID
HGNC:17809
ORF Size (aa)
4257
ORF Size (bp)
4257 bp
RefSeq ID
NM_017575
RefSeq Synonyms
NM_017575, NM_001282326, NM_001256828, NM_001256827, NM_001170957, BC148373, BC064916,
Species
human
UniGene ID
Hs.448342

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.