human SMARCC1 Adenovirus

Name 
Ad-h-SMARCC1
Cat No 
ADV-223718
Availability
4-5 weeks

This is an Adenovirus expressing Human SMARCC1.

ADV-223718
Ad-h-SMARCC1

Ready-to-use Adenovirus expressing Human SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BAF155; BRG1-associated factor 155; chromatin remodeling complex BAF155 subunit; CRACC1; mammalian chromatin remodeling complex BRG1-associated factor 155; Rsc8; SRG3; SWI/SNF complex 155 kDa subunit; SWI/SNF complex subunit SMARCC1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1; SWI3
Description (eCommerce)
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SMARCC1/BAF155 is part of the BAF complex that associates with SMARCA2/Brm and SMARCA4/Brg. The mouse homolog is Srg3 and has been found to be required for embryogenesis and brain development.
Description (Vector)
SMARCC1 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
Gene ID
6599
Gene Name (eCommerce)
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
Gene Name (Vector)
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
Gene Symbol
SMARCC1
HGNC ID
HGNC:11104
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3318
ORF Size (bp)
3318 bp
Protein Name (eCommerce)
SWI/SNF complex subunit SMARCC1
RefSeq ID
NM_003074
RefSeq Synonyms
NM_003074, BC117213, BC113465, BC050564,
Research Areas
Cancer,Chromatin Remodeling,Insulin Signaling,Neurobiology,Neurodevelopment,Neurogenesis,Nuclear Receptor Coactivators,Prostate Cancer,Signal Transduction,TNF Signaling,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,genetics,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SMARCC1/BAF155 is part of the BAF complex that associates with SMARCA2/Brm and SMARCA4/Brg. The mouse homolog is Srg3 and has been found to be required for embryogenesis and brain development.
UniGene ID
Hs.476179
UniProt ID (eCommerce)
Q92922

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.