human AP3M1 Over-expression AAV

Name
AAV-h-AP3M1

Cat No
AAV-201101

Availability
4-5 weeks

This is an AAV expressing Human AP3M1.

AAV-201101

AAV-h-AP3M1

Ready-to-use AAV expressing Human AP3M1 (adaptor related protein complex 3 mu 1 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

AP3M1 is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed.

Gene ID

26985

Gene Name (Vector)

adaptor related protein complex 3 mu 1 subunit

Gene Symbol

AP3M1

HGNC ID

HGNC:569

ORF Size (aa)

1257

ORF Size (bp)

1257 bp

RefSeq ID

NM_012095

RefSeq Synonyms

NM_207012, NM_012095, NM_001320265, NM_001320264, NM_001320263, BC067127, BC026232,

Species

human

UniGene ID

Hs.500104

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.