human SLC16A2 Adenovirus

Name 
Ad-h-SLC16A2
Cat No 
ADV-223129
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SLC16A2.

ADV-223129
Ad-h-SLC16A2

Ready-to-use Adenovirus expressing Human SLC16A2 (solute carrier family 16 member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AHDS; DXS128; DXS128E; MCT 7; MCT 8; MCT7; MCT8; monocarboxylate transporter 7; monocarboxylate transporter 8; MRX22; Solute carrier family 16 member 2; solute carrier family 16, member 2 (thyroid hormone transporter); X-linked PEST-containing transporter; XPCT
Description (eCommerce)
Monocarboxylate transporter 8 (MCT8) is a very active and specific thyroid hormone transporter. It stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. It does not transport Leu, Phe, Trp or Tyr (By similarity)  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P36021].
Description (Vector)
SLC16A2 encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). SLC16A2 is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. SLC16A2 is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome.
Gene ID
6567
Gene Name (eCommerce)
solute carrier family 16 member 2
Gene Name (Vector)
solute carrier family 16 member 2
Gene Symbol
SLC16A2
HGNC ID
HGNC:10923
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1839
ORF Size (bp)
1839 bp
Protein Name (eCommerce)
Monocarboxylate transporter 8
RefSeq ID
NM_006517
RefSeq Synonyms
NM_006517, BC156880, BC156062,
Research Areas
Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Monocarboxylate transporter 8 (MCT8) is a very active and specific thyroid hormone transporter. It stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. It does not transport Leu, Phe, Trp or Tyr (By similarity)  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P36021].
UniGene ID
Hs.75317
UniProt ID (eCommerce)
P36021

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.