human SLC10A2 Adenovirus
This is an Adenovirus expressing Human SLC10A2.
ADV-223072
Ad-h-SLC10A2
Ready-to-use Adenovirus expressing Human SLC10A2 (solute carrier family 10 member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ASBT; IBAT; ISBT; NTCP2; PBAM
Description (Vector)
SLC10A2 encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).
Gene ID
6555
Gene Name (Vector)
solute carrier family 10 member 2
Gene Symbol
SLC10A2
HGNC ID
HGNC:10906
ORF Size (aa)
1047
RefSeq ID
NM_000452
RefSeq Synonyms
NM_000452, BC130523, BC130521,
Species
human
UniGene ID
Hs.194783
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.