human SIGLEC8 Adenovirus
This is an Adenovirus expressing Human SIGLEC8.
ADV-222995
Ad-h-SIGLEC8
Ready-to-use Adenovirus expressing Human SIGLEC8 (sialic acid binding Ig like lectin 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SAF2; SIGLEC-8; SIGLEC8L
Description (Vector)
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 (PubMed 11095983)).(supplied by OMIM, May 2010)
Gene ID
27181
Gene Name (Vector)
sialic acid binding Ig like lectin 8
Gene Symbol
SIGLEC8
HGNC ID
HGNC:10877
ORF Size (aa)
1500
ORF Size (bp)
1500 bp
RefSeq ID
NM_014442
RefSeq Synonyms
NM_014442, BC053319,
Species
human
UniGene ID
Hs.447899
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.