human AOC2 Over-expression AAV

Name 
AAV-h-AOC2
Cat No 
AAV-201069
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AOC2.

AAV-201069
AAV-h-AOC2

Ready-to-use AAV expressing Human AOC2 (amine oxidase, copper containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DAO2; RAO; SSAO
Description (Vector)
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.
Gene ID
314
Gene Name (Vector)
amine oxidase, copper containing 2
Gene Symbol
AOC2
HGNC ID
HGNC:549
ORF Size (aa)
2271
ORF Size (bp)
2271 bp
RefSeq ID
NM_001158
RefSeq Synonyms
NM_009590, NM_001158, BC142641,
Species
human
UniGene ID
Hs.143102

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.