human SIGLEC5 Adenovirus

Name 
Ad-h-SIGLEC5
Cat No 
ADV-222991
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SIGLEC5.

ADV-222991
Ad-h-SIGLEC5

Ready-to-use Adenovirus expressing Human SIGLEC5 (sialic acid binding Ig like lectin 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD170; CD33L2; OB-BP2; OBBP2; SIGLEC-5
Description (Vector)
SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
Gene ID
8778
Gene Name (Vector)
sialic acid binding Ig like lectin 5
Gene Symbol
SIGLEC5
HGNC ID
HGNC:10874
ORF Size (aa)
1656
ORF Size (bp)
1656 bp
RefSeq ID
NM_003830
RefSeq Synonyms
NM_003830, BC029896,
Species
human
UniGene ID
Hs.310333

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.