human SGSH Adenovirus

Name 
Ad-h-SGSH
Cat No 
ADV-222869
Availability
4-5 weeks

This is an Adenovirus expressing Human INHBE.

ADV-222869
Ad-h-SGSH

Ready-to-use Adenovirus expressing Human SGSH (N-sulfoglucosamine sulfohydrolase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HSS; MPS3A; SFMD
Description (Vector)
SGSH encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined.
Gene ID
6448
Gene Name (Vector)
N-sulfoglucosamine sulfohydrolase
Gene Symbol
SGSH
HGNC ID
HGNC:10818
ORF Size (aa)
1509
ORF Size (bp)
1509 bp
RefSeq ID
NM_000199
RefSeq Synonyms
NM_000199, BC047318,
Species
human
UniGene ID
Hs.31074

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.