human SDHB Adenovirus
This is an Adenovirus expressing Human SDHB.
ADV-222438
Ad-h-SDHB
Ready-to-use Adenovirus expressing Human SDHB (succinate dehydrogenase complex iron sulfur subunit B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP
Description (Vector)
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Gene ID
6390
Gene Name (Vector)
succinate dehydrogenase complex iron sulfur subunit B
Gene Symbol
SDHB
HGNC ID
HGNC:10681
ORF Size (aa)
843
ORF Size (bp)
843 bp
RefSeq ID
NM_003000
RefSeq Synonyms
NM_003000, BC007840,
Species
human
UniGene ID
Hs.465924
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.