human SAPS2 Adenovirus

Name 
Ad-h-SAPS2
Cat No 
ADV-222241
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SAPS2.

ADV-222241
Ad-h-SAPS2

Ready-to-use Adenovirus expressing Human PPP6R2 (protein phosphatase 6 regulatory subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
KIAA0685; PP6R2; SAP190; SAPS domain family member 2; SAPS domain family, member 2; SAPS2; serine/threonine-protein phosphatase 6 regulatory subunit 2
Description (eCommerce)
SAPS2 is a regulatory subunit of the PP6 phosphatase. There are 3 human SAPs (sit4-associated proteins), SAPS1, SAPS2, and SAPS3. The human SAPs are related to SAPs found in yeast that associate with the sit4 phosphatase which is the homolog of human PP6 phosphatase. In yeast sit4 and its associated SAPs are involved in a variety of processes which include transcription, translation, bud formation, glycogen metabolism, ion homeostasis, and telomere function.SAPS2 has been identified as gene induced by beta1-integrin ligation on B-cells and by interleukin 13 in airway smooth muscle.
Description (Vector)
Protein phosphatase regulatory subunits, such as SAPS2, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS2 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 (PubMed 16769727)).(supplied by OMIM, Nov 2010)
Gene ID
9701
Gene Name (eCommerce)
protein phosphatase 6 regulatory subunit 2
Gene Name (Vector)
protein phosphatase 6 regulatory subunit 2
Gene Symbol
PPP6R2
HGNC ID
HGNC:19253
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2802
ORF Size (bp)
2802 bp
Protein Name (eCommerce)
Serine/threonine-protein phosphatase 6 regulatory subunit 2
RefSeq ID
NM_014678
RefSeq Synonyms
NM_014678, NM_001242900, NM_001242899, NM_001242898, BC052995, BC041698, BC032664, BC006568, BC000976,
Research Areas
Kinase/Phosphatase
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
SAPS2 is a regulatory subunit of the PP6 phosphatase. There are 3 human SAPs (sit4-associated proteins), SAPS1, SAPS2, and SAPS3. The human SAPs are related to SAPs found in yeast that associate with the sit4 phosphatase which is the homolog of human PP6 phosphatase. In yeast sit4 and its associated SAPs are involved in a variety of processes which include transcription, translation, bud formation, glycogen metabolism, ion homeostasis, and telomere function.SAPS2 has been identified as gene induced by beta1-integrin ligation on B-cells and by interleukin 13 in airway smooth muscle.
UniGene ID
Hs.449098
UniProt ID (eCommerce)
O75170

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.