human RPS6KA1 Adenovirus

Name 
Ad-h-RPS6KA1
Cat No 
ADV-221933
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RPS6KA1.

ADV-221933
Ad-h-RPS6KA1

Ready-to-use Adenovirus expressing Human RPS6KA1 (ribosomal protein S6 kinase A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK1A; MAPKAPK-1a; p90Rsk; p90-RSK 1; p90RSK1; p90S6K; ribosomal protein S6 kinase alpha-1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal S6 kinase 1; RSK; RSK1; RSK-1; S6K-alpha 1; S6K-alpha-1
Description (eCommerce)
Ribosomal protein S6 kinase alpha-1 (RSK1) is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. RSK1 kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation [taken from NCBI Entrez Gene (GeneID: 6195)].
Description (Vector)
RPS6KA1 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
6195
Gene Name (eCommerce)
ribosomal protein S6 kinase A1
Gene Name (Vector)
ribosomal protein S6 kinase A1
Gene Symbol
RPS6KA1
HGNC ID
HGNC:10430
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2208
ORF Size (bp)
2208 bp
Protein Name (eCommerce)
Ribosomal protein S6 kinase alpha-1
RefSeq ID
NM_002953
RefSeq Synonyms
NM_002953, NM_001330441, NM_001006665, BC014966,
Research Areas
Apoptosis,Axon Guidance,B-cell Receptor Signaling,BDNF Signaling,Cardiac Hypertrophy,Cardiology,Cardiovascular,Cell Cycle,EGFR Signaling,EPO Signaling,FGF Signaling,GPCR Signaling,Immunology,Innate Immunity,Insulin Signaling,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,MAPK Signaling,Meiosis,mTOR Signaling,Neurobiology,NGF Signaling,SCF-KIT Signaling,Signal Transduction,Toll-like Receptor Signaling,Transcription Factor/Regulator,Translational Control,TSH Signaling,VEGF Signaling,Wnt Signaling
Research Areas (Faceted)
cardiovascular,cell_biology,cell_cycle,developmental_biology,genetics,immunology,neurobiology,signal_transduction,stem_cell_biology,transcription_translation
Species
human
Target Sentence
Ribosomal protein S6 kinase alpha-1 (RSK1) is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. RSK1 kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation [taken from NCBI Entrez Gene (GeneID: 6195)].
UniGene ID
Hs.149957
UniProt ID (eCommerce)
Q15418

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.