human RNF111 Adenovirus
This is an Adenovirus expressing Human RNF111.
ADV-221327
Ad-h-RNF111
Ready-to-use Adenovirus expressing Human RNF111 (ring finger protein 111). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARK
Description (Vector)
RNF111 is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Gene ID
54778
Gene Name (Vector)
ring finger protein 111
Gene Symbol
RNF111
HGNC ID
HGNC:17384
ORF Size (aa)
2958
ORF Size (bp)
2958 bp
RefSeq ID
NM_017610
RefSeq Synonyms
NM_017610, NM_001330331, NM_001270530, NM_001270529, NM_001270528, BC060862, BC010369,
Species
human
UniGene ID
Hs.404423
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.