human RIMS1 Adenovirus

Name 
Ad-h-RIMS1
Cat No 
ADV-221237
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human HNRNPLL.

ADV-221237
Ad-h-RIMS1

Ready-to-use Adenovirus expressing Human RIMS1 (regulating synaptic membrane exocytosis 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CORD7; Rab-3-interacting molecule 1; rab3-interacting molecule 1; rab-3-interacting protein 2; RAB3-interacting protein 2; RAB3IP2; regulating synaptic membrane exocytosis protein 1; RIM; RIM 1; RIM1
Description (eCommerce)
RIMS1 is a Rab effector involved in exocytosis (By similarity). It may act as scaffold protein that regulates neurotransmitter release at the active zone. RIMS1 is ssential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86UR5].
Description (Vector)
RIMS1 is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene.
Gene ID
22999
Gene Name (eCommerce)
regulating synaptic membrane exocytosis 1
Gene Name (Vector)
regulating synaptic membrane exocytosis 1
Gene Symbol
RIMS1
HGNC ID
HGNC:17282
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5076
ORF Size (bp)
5076 bp
Protein Name (eCommerce)
Regulating synaptic membrane exocytosis protein 1
RefSeq ID
NM_014989
RefSeq Synonyms
NM_014989, NM_001168411, NM_001168410, NM_001168409, NM_001168408, NM_001168407, BC172482, BC156411, BC152435, BC151853,
Research Areas
Neurobiology,Synapse,Zinc-finger
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
RIMS1 is a Rab effector involved in exocytosis (By similarity). It may act as scaffold protein that regulates neurotransmitter release at the active zone. RIMS1 is ssential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86UR5].
UniGene ID
Hs.485729
UniProt ID (eCommerce)
Q86UR5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.