human QKI Adenovirus
This is an Adenovirus expressing Human QKI.
ADV-220466
Ad-h-QKI
Ready-to-use Adenovirus expressing Human QKI (QKI, KH domain containing RNA binding). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
homolog of mouse quaking QKI (KH domain RNA binding protein); Hqk; hqkI; protein quaking; QK; QK1; QK3; QKI/LOC100132735 fusion; quaking homolog, KH domain RNA binding; RNA binding protein HQK
Description (eCommerce)
QKI is an RNA-binding protein and translational repressor important to embryogenesis and myelination. QKI exist as multiple isoforms with distinct functions that regulate pre-mRNA splicing and the stability of proteins central to oligodendrocyte differentiation. QKI has been identified as a candidate gene in schizophrenia.
Description (Vector)
QKI is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Four transcript variants encoding different isoforms have been found for this gene.
Gene ID
9444
Gene Name (eCommerce)
QKI, KH domain containing RNA binding
Gene Name (Vector)
QKI, KH domain containing RNA binding
Gene Symbol
QKI
HGNC ID
HGNC:21100
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1026
ORF Size (bp)
1026 bp
Protein Name (eCommerce)
Protein quaking
RefSeq ID
NM_006775
RefSeq Synonyms
NM_206855, NM_206854, NM_206853, NM_006775, NM_001301085, BC019917,
Research Areas
Cardiovascular,Gene Expression,mRNA Processing,mRNA Splicing,mRNA transport,Neurobiology,Nuclear Import/Export,RNA Binding,RNA Processing,RNA Transport,Translational Control,Transport
Research Areas (Faceted)
cardiovascular,genetics,transcription_translation,neurobiology,cell_biology,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
QKI is an RNA-binding protein and translational repressor important to embryogenesis and myelination. QKI exist as multiple isoforms with distinct functions that regulate pre-mRNA splicing and the stability of proteins central to oligodendrocyte differentiation. QKI has been identified as a candidate gene in schizophrenia.
UniGene ID
Hs.593520
UniProt ID (eCommerce)
Q96PU8
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.