human PRKAG3 Adenovirus

Name 
Ad-h-PRKAG3
Cat No 
ADV-219847
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PRKAG3.

ADV-219847
Ad-h-PRKAG3

Ready-to-use Adenovirus expressing Human PRKAG3 (protein kinase AMP-activated non-catalytic subunit gamma 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AMPKG3
Description (Vector)
PRKAG3 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Gene ID
53632
Gene Name (Vector)
protein kinase AMP-activated non-catalytic subunit gamma 3
Gene Symbol
PRKAG3
HGNC ID
HGNC:9387
ORF Size (aa)
1470
ORF Size (bp)
1470 bp
RefSeq ID
NM_017431
RefSeq Synonyms
NM_017431, BC098306, BC098277, BC098255, BC098102,
Species
human
UniGene ID
Hs.591634

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.