human PHKA1 Adenovirus
This is an Adenovirus expressing Human PHKA1.
ADV-218829
Ad-h-PHKA1
Ready-to-use Adenovirus expressing Human PHKA1 (phosphorylase kinase regulatory subunit alpha 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PHKA
Description (Vector)
Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.
Gene ID
5255
Gene Name (Vector)
phosphorylase kinase regulatory subunit alpha 1
Gene Symbol
PHKA1
HGNC ID
HGNC:8925
ORF Size (aa)
3456
ORF Size (bp)
3456 bp
RefSeq ID
NM_002637
RefSeq Synonyms
NM_002637, NM_001172436, NM_001122670, BC143501, BC143499, BC104944,
Species
human
UniGene ID
Hs.201379
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.