human PDHB Adenovirus
This is an Adenovirus expressing Human PDHB.
ADV-218518
Ad-h-PDHB
Ready-to-use Adenovirus expressing Human PDHB (pyruvate dehydrogenase (lipoamide) beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PDHBD; PDHE1-B; PHE1B
Description (Vector)
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene.
Gene ID
5162
Gene Name (Vector)
pyruvate dehydrogenase (lipoamide) beta
Gene Symbol
PDHB
HGNC ID
HGNC:8808
ORF Size (aa)
1080
RefSeq ID
NM_000925
RefSeq Synonyms
NM_001315536, NM_001173468, NM_000925, BC001924, BC000439,
Species
human
UniGene ID
Hs.161357
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.