human AGRP Over-expression AAV

Name 
AAV-h-AGRP
Cat No 
AAV-200580
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AGRP.

AAV-200580
AAV-h-AGRP

Ready-to-use AAV expressing Human AGRP (agouti related neuropeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AGRT; ART; ASIP2
Description (Vector)
AGRP encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
Gene ID
181
Gene Name (Vector)
agouti related neuropeptide
Gene Symbol
AGRP
HGNC ID
HGNC:330
ORF Size (aa)
399
ORF Size (bp)
399 bp
RefSeq ID
NM_001138
RefSeq Synonyms
NM_001138, BC110443,
Species
human
UniGene ID
Hs.104633

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.