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human PAXIP1 Adenovirus

Name 
Ad-h-PAXIP1
Cat No 
ADV-218284
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PAXIP1.

ADV-218284
Ad-h-PAXIP1

Ready-to-use Adenovirus expressing Human PAXIP1 (PAX interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAGF28; CAGF29; PACIP1; PAX interacting (with transcription-activation domain) protein 1; PAX transactivation activation domain-interacting protein; PAX transcription activation domain interacting protein 1 like; PAX-interacting protein 1; PAXIP1L; protein encoded by CAG trinucleotide repeats; PTIP; TNRC2
Description (eCommerce)
Pax transactivation domain-interacting protein (PTIP) is implicated in the DNA damage response. PTIP interacts with 53BP1 and PA1 and is part of a Set1-like histone methyltransferase (HMT) complex that also contains ASH2L, RBBP5, WDR5, hDPY-30, NCOA6, a novel protein PA-1 MLL3, MLL4, and UTX. PTIP is therefore suggested to have a role in the regulation of gene expression.
Description (Vector)
PAXIP1 is a member of the paired box (PAX) gene family and encodes a nuclear protein with six BRCT (breast cancer carboxy-terminal) domains. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis.
Gene ID
22976
Gene Name (eCommerce)
PAX interacting protein 1
Gene Name (Vector)
PAX interacting protein 1
Gene Symbol
PAXIP1
HGNC ID
HGNC:8624
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2274
ORF Size (bp)
2274 bp
Protein Name (eCommerce)
PAX-interacting protein 1
RefSeq ID
NM_007349
RefSeq Synonyms
NM_007349, BC033781,
Research Areas
Cardiovascular,DNA Damage/Repair,Histone Modification,Transcription Factor/Regulator
Research Areas (Faceted)
cardiovascular,cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Pax transactivation domain-interacting protein (PTIP) is implicated in the DNA damage response. PTIP interacts with 53BP1 and PA1 and is part of a Set1-like histone methyltransferase (HMT) complex that also contains ASH2L, RBBP5, WDR5, hDPY-30, NCOA6, a novel protein PA-1 MLL3, MLL4, and UTX. PTIP is therefore suggested to have a role in the regulation of gene expression.
UniGene ID
Hs.443881
UniProt ID (eCommerce)
Q6ZW49

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.