human AGPS Over-expression AAV

Name
AAV-h-AGPS

Cat No
AAV-200577

Availability
4-5 weeks

This is an AAV expressing Human AGPS.

AAV-200577

AAV-h-AGPS

Ready-to-use AAV expressing Human AGPS (alkylglycerone phosphate synthase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ADAP-S; ADAS; ADHAPS; ADPS; ALDHPSY; RCDP3

Description (Vector)

AGPS is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.

Gene ID

8540

Gene Name (Vector)

alkylglycerone phosphate synthase

Gene Symbol

AGPS

HGNC ID

HGNC:327

ORF Size (aa)

1977

ORF Size (bp)

1977 bp

RefSeq ID

NM_003659

RefSeq Synonyms

NM_003659, BC141820,

Species

human

UniGene ID

Hs.516543

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.