human PPAN Adenovirus

Name 
Ad-h-PPAN
Cat No 
ADV-218056
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PPAN.

ADV-218056
Ad-h-PPAN

Ready-to-use Adenovirus expressing Human PPAN (peter pan homolog (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
brix domain-containing protein 3; BXDC3; homolog of S. cerevisiae SSF1; Peter Pan homolog; second-step splicing factor 1; SSF; SSF1; SSF-1; SSF2; suppressor of sterile four 1; suppressor of SWI4 1 homolog
Description (eCommerce)
Peter Pan homolog (PPAN) is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells [taken from NCBI Entrez Gene (Gene ID: 56342)].
Description (Vector)
PPAN is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
Gene ID
56342
Gene Name (eCommerce)
peter pan homolog
Gene Name (Vector)
peter pan homolog (Drosophila)
Gene Symbol
PPAN
HGNC ID
HGNC:9227
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1422
ORF Size (bp)
1422 bp
Protein Name (eCommerce)
Suppressor of SWI4 1 homolog
RefSeq ID
NM_020230
RefSeq Synonyms
NM_020230, NM_001346141, NM_001346140, NM_001346139, BC033202, BC009833,
Research Areas
GPCR Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Peter Pan homolog (PPAN) is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells [taken from NCBI Entrez Gene (Gene ID: 56342)].
UniGene ID
Hs.14468
UniProt ID (eCommerce)
Q9NQ55

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.