human NLRP4 Adenovirus
This is an Adenovirus expressing Human FCGR2A.
ADV-216804
Ad-h-NLRP4
Ready-to-use Adenovirus expressing Human NLRP4 (NLR family pyrin domain containing 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CLR19.5; CT58; NALP4; PAN2; PYPAF4; RNH2
Description (Vector)
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 (PubMed 12563287)).(supplied by OMIM, Mar 2008)
Gene ID
147945
Gene Name (Vector)
NLR family pyrin domain containing 4
Gene Symbol
NLRP4
HGNC ID
HGNC:22943
ORF Size (aa)
2985
ORF Size (bp)
2985 bp
RefSeq ID
NM_134444
RefSeq Synonyms
NM_134444, BC050326,
Species
human
UniGene ID
Hs.631533
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.