human NLRP13 Adenovirus
This is an Adenovirus expressing Human NLRP13.
ADV-216795
Ad-h-NLRP13
Ready-to-use Adenovirus expressing Human NLRP13 (NLR family pyrin domain containing 13). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CLR19.7; NALP13; NOD14; PAN13
Description (Vector)
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 (PubMed 12563287)).(supplied by OMIM, Mar 2008)
Gene ID
126204
Gene Name (Vector)
NLR family pyrin domain containing 13
Gene Symbol
NLRP13
HGNC ID
HGNC:22937
ORF Size (aa)
3129
ORF Size (bp)
3129 bp
RefSeq ID
NM_176810
RefSeq Synonyms
NM_176810, NM_001321057, BC148742, BC146295,
Species
human
UniGene ID
Hs.446924
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.