human NEK3 Adenovirus

Name 
Ad-h-NEK3
Cat No 
ADV-216571
Availability
4-5 weeks

This is an Adenovirus expressing Human NEK3.

ADV-216571
Ad-h-NEK3

Ready-to-use Adenovirus expressing Human NEK3 (NIMA related kinase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HSPK36
Description (Vector)
NEK3 encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
4752
Gene Name (Vector)
NIMA related kinase 3
Gene Symbol
NEK3
HGNC ID
HGNC:7746
ORF Size (aa)
1521
ORF Size (bp)
1521 bp
RefSeq ID
NM_152720
RefSeq Synonyms
NM_152720, NM_002498, NM_001146099, BC019916,
Species
human
UniGene ID
Hs.409989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.