human ADAM8 Over-expression AAV

Name 
AAV-h-ADAM8
Cat No 
AAV-200371
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ADAM8.

AAV-200371
AAV-h-ADAM8

Ready-to-use AAV expressing Human ADAM8 (ADAM metallopeptidase domain 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD156; CD156a; MS2
Description (Vector)
ADAM8 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.
Gene ID
101
Gene Name (Vector)
ADAM metallopeptidase domain 8
Gene Symbol
ADAM8
HGNC ID
HGNC:215
ORF Size (aa)
2475
ORF Size (bp)
2475 bp
RefSeq ID
NM_001109
RefSeq Synonyms
NM_001164490, NM_001164489, NM_001109, BC115404,
Species
human
UniGene ID
Hs.501574

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.