human NCAM1 Adenovirus

Name 
Ad-h-NCAM1
Cat No 
ADV-216379
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human NCAM1.

ADV-216379
Ad-h-NCAM1

Ready-to-use Adenovirus expressing Human NCAM1 (neural cell adhesion molecule 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
antigen recognized by monoclonal antibody 5.1H11; CD antigen CD56; CD56; MSK39; NCAM; N-CAM-1; NCAM-1; neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM
Description (eCommerce)
NCAM1, is a cell adhesion protein of the immunoglobulin superfamily that is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. It plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. NCAM1 is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. One prominent isoform NCAM1, known as cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients. [taken from NCBI Entrez Gene (Gene ID: 4684)].
Description (Vector)
NCAM1 encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants.
Gene ID
4684
Gene Name (eCommerce)
neural cell adhesion molecule 1
Gene Name (Vector)
neural cell adhesion molecule 1
Gene Symbol
NCAM1
HGNC ID
HGNC:7656
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2577
ORF Size (bp)
2577 bp
Protein Name (eCommerce)
Neural cell adhesion molecule 1
RefSeq ID
NM_000615
RefSeq Synonyms
NM_181351, NM_001242608, NM_001242607, NM_001076682, NM_000615, BC047244,
Research Areas
Axon Guidance,BDNF Signaling,Cardiac Development,Cardiology,Cardiovascular,FGF Signaling,Golgi Apparatus,IFN Signaling,Immunology,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,neurobiology,immunology,cardiovascular,signal_transduction,developmental_biology,cell_biology,immunology,signal_transduction,neurobiology
Species
human
Target Sentence
NCAM1, is a cell adhesion protein of the immunoglobulin superfamily that is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. It plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. NCAM1 is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. One prominent isoform NCAM1, known as cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients. [taken from NCBI Entrez Gene (Gene ID: 4684)].
UniGene ID
Hs.503878
UniProt ID (eCommerce)
P13591

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.