human NAGS Adenovirus

Name 
Ad-h-NAGS
Cat No 
ADV-216293
Availability
4-5 weeks

This is an Adenovirus expressing Human NAGS.

ADV-216293
Ad-h-NAGS

Ready-to-use Adenovirus expressing Human NAGS (N-acetylglutamate synthase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AGAS; ARGA
Description (Vector)
The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Gene ID
162417
Gene Name (Vector)
N-acetylglutamate synthase
Gene Symbol
NAGS
HGNC ID
HGNC:17996
ORF Size (aa)
1107
RefSeq ID
NM_153006
RefSeq Synonyms
NM_153006, BC111713,
Species
human
UniGene ID
Hs.8876

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.