human ADAM11 Over-expression AAV

Name
AAV-h-ADAM11

Cat No
AAV-200346

Availability
4-5 weeks

This is an AAV expressing Human ADAM11.

AAV-200346

AAV-h-ADAM11

Ready-to-use AAV expressing Human ADAM11 (ADAM metallopeptidase domain 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MDC

Description (Vector)

ADAM11 encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM11 represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.

Gene ID

4185

Gene Name (Vector)

ADAM metallopeptidase domain 11

Gene Symbol

ADAM11

HGNC ID

HGNC:189

ORF Size (aa)

2307

ORF Size (bp)

2307 bp

RefSeq ID

NM_002390

RefSeq Synonyms

NM_002390, NM_001318933, BC111916,

Species

human

UniGene ID

Hs.6088

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.