human MTRR Adenovirus
This is an Adenovirus expressing Human MTRR.
ADV-216052
Ad-h-MTRR
Ready-to-use Adenovirus expressing Human MTRR (5-methyltetrahydrofolate-homocysteine methyltransferase reductase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cblE; MSR
Description (Vector)
Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Gene ID
4552
Gene Name (Vector)
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Gene Symbol
MTRR
HGNC ID
HGNC:7473
ORF Size (aa)
2097
ORF Size (bp)
2097 bp
RefSeq ID
NM_002454
RefSeq Synonyms
NM_024010, NM_002454, BC109216, BC054816,
Species
human
UniGene ID
Hs.481551
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.