human ACVR1C Over-expression AAV

Name
AAV-h-ACVR1C

Cat No
AAV-200325

Availability
4-5 weeks

This is an AAV expressing Human ACVR1C.

AAV-200325

AAV-h-ACVR1C

Ready-to-use AAV expressing Human ACVR1C (activin A receptor type 1C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACVRLK7; ALK7

Description (Vector)

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 (PubMed 12063393)).(supplied by OMIM, Mar 2008)

Gene ID

130399

Gene Name (Vector)

activin A receptor type 1C

Gene Symbol

ACVR1C

HGNC ID

HGNC:18123

ORF Size (aa)

1482

ORF Size (bp)

1482 bp

RefSeq ID

NM_145259

RefSeq Synonyms

NM_145259, NM_001111033, NM_001111032, NM_001111031, BC022530,

Species

human

UniGene ID

Hs.562901

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.