human MED13L Adenovirus

Name 
Ad-h-MED13L
Cat No 
ADV-215238
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human EPHA6.

ADV-215238
Ad-h-MED13L

Ready-to-use Adenovirus expressing Human MED13L (mediator complex subunit 13 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Mediator complex subunit 13-like; mediator of RNA polymerase II transcription subunit 13-like; MRFACD; PROSIT240; THRAP2; thyroid hormone receptor-associated protein 2; thyroid hormone receptor-associated protein complex 240 kDa component-like; TRAP240L
Description (eCommerce)
Mediator complex subunit 13-like is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q71F56].
Description (Vector)
MED13L is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).
Gene ID
23389
Gene Name (eCommerce)
mediator complex subunit 13 like
Gene Name (Vector)
mediator complex subunit 13 like
Gene Symbol
MED13L
HGNC ID
HGNC:22962
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
6633
ORF Size (bp)
6633 bp
Protein Name (eCommerce)
Mediator of RNA polymerase II transcription subunit 13-like
RefSeq ID
NM_015335
RefSeq Synonyms
NM_015335, BC130422,
Research Areas
Metabolism/Metabolic Process,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Mediator complex subunit 13-like is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q71F56].
UniGene ID
Hs.715095
UniProt ID (eCommerce)
Q71F56

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.