human ACCN4 Over-expression AAV

Name 
AAV-h-ACCN4
Cat No 
AAV-200176
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ASIC4.

AAV-200176
AAV-h-ACCN4

Ready-to-use AAV expressing Human ASIC4 (acid sensing ion channel subunit family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACCN4; BNAC4
Description (Vector)
ASIC4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. ASIC4 is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC.
Gene ID
55515
Gene Name (Vector)
acid sensing ion channel subunit family member 4
Gene Symbol
ASIC4
HGNC ID
HGNC:21263
ORF Size (aa)
1944
ORF Size (bp)
1944 bp
RefSeq ID
NM_018674
RefSeq Synonyms
NM_182847, NM_018674, BC031812, BC010439,
Species
human
UniGene ID
Hs.87469

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.