human LMAN1 Adenovirus
This is an Adenovirus expressing Human RIPPLY3.
ADV-214006
Ad-h-LMAN1
Ready-to-use Adenovirus expressing Human LMAN1 (lectin, mannose binding 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
endoplasmic reticulum-golgi intermediate compartment protein 53; ERGIC53; ERGIC-53; ER-Golgi intermediate compartment 53 kDa protein; F5F8D; FMFD1; gp58; intracellular mannose-specific lectin MR60; Lectin mannose-binding 1; MCFD1; MR60; protein ERGIC-53
Description (eCommerce)
Lectin mannose-binding 1 (LMAN1) is a mannose-specific lectin. LMAN1 may recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P49257].
Description (Vector)
LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Gene ID
3998
Gene Name (eCommerce)
lectin, mannose binding 1
Gene Name (Vector)
lectin, mannose binding 1
Gene Symbol
LMAN1
HGNC ID
HGNC:6631
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1533
ORF Size (bp)
1533 bp
Protein Name (eCommerce)
Protein ERGIC-53
RefSeq ID
NM_005570
RefSeq Synonyms
NM_005570, BC032330,
Research Areas
Golgi Apparatus,Metabolism/Metabolic Process,Protein Folding,Signal Transduction,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
Lectin mannose-binding 1 (LMAN1) is a mannose-specific lectin. LMAN1 may recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P49257].
UniGene ID
Hs.465295
UniProt ID (eCommerce)
P49257
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.