human ABI2 Over-expression AAV

Name 
AAV-h-ABI2
Cat No 
AAV-200124
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ABI2.

AAV-200124
AAV-h-ABI2

Ready-to-use AAV expressing Human ABI2 (abl interactor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
abelson interactor 2; ABI-2; ABI2B; abl binding protein 3; abl interactor 2; Abl-binding protein 3; AblBP3; abl-interacting protein 1 (SH3-containing protein); abl-interactor protein 2b; AIP1; AIP-1; arg protein tyrosine kinase-binding protein; arg-binding protein 1; argBP1; argBPIA; argBPIB; SSH3BP2
Description (eCommerce)
Abelson interactor 2 (Abi-2) may act in the regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Abi-2 regulates ABL1/c-Abl-mediated phosphorylation of MENA, and may be involved in cytoskeletal reorganization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NYB9].
Gene ID
10152
Gene Name (eCommerce)
abl interactor 2
Gene Name (Vector)
abl interactor 2
Gene Symbol
ABI2
HGNC ID
HGNC:24011
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1428
ORF Size (bp)
1428 bp
Protein Name (eCommerce)
Abl interactor 2
RefSeq ID
NM_005759
RefSeq Synonyms
NM_005759, NM_001282932, NM_001282927, NM_001282926, NM_001282925, BC001439,
Research Areas
Cytoskeleton,Immunology,Innate Immunity,RAC1 Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,immunology,signal_transduction
Species
human
Target Sentence
Abelson interactor 2 (Abi-2) may act in the regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Abi-2 regulates ABL1/c-Abl-mediated phosphorylation of MENA, and may be involved in cytoskeletal reorganization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NYB9].
UniGene ID
Hs.471156
UniProt ID (eCommerce)
Q9NYB9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.