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human LILRB1 Adenovirus

Name 
Ad-h-LILRB1
Cat No 
ADV-213933
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human LILRB1.

ADV-213933
Ad-h-LILRB1

Ready-to-use Adenovirus expressing Human LILRB1 (leukocyte immunoglobulin like receptor B1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD85J; ILT-2; ILT2; LIR-1; LIR1; MIR-7; MIR7; PIR-B; PIRB
Description (Vector)
LILRB1 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
10859
Gene Name (Vector)
leukocyte immunoglobulin like receptor B1
Gene Symbol
LILRB1
HGNC ID
HGNC:6605
ORF Size (aa)
1953
ORF Size (bp)
1953 bp
RefSeq ID
NM_006669
RefSeq Synonyms
NM_006669, NM_001278399, NM_001278398, NM_001081639, NM_001081638, NM_001081637, BC015731,
Species
human
UniGene ID
Hs.667388

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.