human LEPRE1 Adenovirus
This is an Adenovirus expressing Human LEPRE1.
ADV-213835
Ad-h-LEPRE1
Ready-to-use Adenovirus expressing Human P3H1 (prolyl 3-hydroxylase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GROS1; growth suppressor 1; LEPRE1; leprecan; Leprecan-1; leucine- and proline-enriched proteoglycan 1; leucine proline-enriched proteoglycan (leprecan) 1; OI8; procollagen-proline 3-dioxygenase; prolyl 3-hydroxylase 1
Description (eCommerce)
LEPRE1/GROS1 is an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly [taken from NCBI Entrez Gene (Gene ID: 64175)].
Description (Vector)
LEPRE1 encodes an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly. Mutations in this gene are associated with osteogenesis imperfecta type VIII. Three alternatively spliced transcript variants encoding different isoforms have been described. Other variants may exist, but their biological validity has not been determined.
Gene ID
64175
Gene Name (eCommerce)
prolyl 3-hydroxylase 1
Gene Name (Vector)
prolyl 3-hydroxylase 1
Gene Symbol
P3H1
HGNC ID
HGNC:19316
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2094
ORF Size (bp)
2094 bp
Protein Name (eCommerce)
Prolyl 3-hydroxylase 1
RefSeq ID
NM_022356
RefSeq Synonyms
NM_022356, NM_001243246, NM_001146289, BC108311,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
LEPRE1/GROS1 is an enzyme that is a member of the collagen prolyl hydroxylase family. These enzymes are localized to the endoplasmic reticulum and their activity is required for proper collagen synthesis and assembly [taken from NCBI Entrez Gene (Gene ID: 64175)].
UniGene ID
Hs.437656
UniProt ID (eCommerce)
Q32P28
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.