human ABCB7 Over-expression AAV

Name
AAV-h-ABCB7

Cat No
AAV-200062

Availability
4-5 weeks

This is an AAV expressing Human ABCB7.

AAV-200062

AAV-h-ABCB7

Ready-to-use AAV expressing Human ABCB7 (ATP binding cassette subfamily B member 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABC7; ASAT; Atm1p; EST140535

Description (Vector)

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.

Gene ID

Gene Name (Vector)

ATP binding cassette subfamily B member 7

Gene Symbol

ABCB7

HGNC ID

HGNC:48

ORF Size (aa)

2262

ORF Size (bp)

2262 bp

RefSeq ID

NM_004299

RefSeq Synonyms

NM_004299, NM_001271699, NM_001271698, NM_001271697, NM_001271696, BC006323,

Species

human

UniGene ID

Hs.370480

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.