human KLK7 Adenovirus

Name 
Ad-h-KLK7
Cat No 
ADV-213303
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human KLK7.

ADV-213303
Ad-h-KLK7

Ready-to-use Adenovirus expressing Human KLK7 (kallikrein related peptidase 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hK7; PRSS6; SCCE
Description (Vector)
KLK7 encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.
Gene ID
5650
Gene Name (Vector)
kallikrein related peptidase 7
Gene Symbol
KLK7
HGNC ID
HGNC:6368
ORF Size (aa)
762
ORF Size (bp)
762 bp
RefSeq ID
NM_005046
RefSeq Synonyms
NM_139277, NM_005046, NM_001243126, NM_001207053, BC032005,
Species
human
UniGene ID
Hs.151254

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.