human KDM5C Adenovirus

Name 
Ad-h-KDM5C
Cat No 
ADV-212853
Availability
4-5 weeks

This is an Adenovirus expressing Human KDM5C.

ADV-212853
Ad-h-KDM5C

Ready-to-use Adenovirus expressing Human KDM5C (lysine demethylase 5C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DXS1272E; histone demethylase JARID1C; JARID1C; JmjC domain-containing protein SMCX; Jumonji, AT rich interactive domain 1C (RBP2-like); Jumonji/ARID domain-containing protein 1C; lysine (K)-specific demethylase 5C; lysine-specific demethylase 5C; MRX13; MRXJ; MRXSCJ; MRXSJ; Protein SmcX; Protein Xe169; SMCX; Smcx homolog, X chromosome; Smcy homolog, X-linked; XE169
Description (eCommerce)
JARID1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. Mutations in JARID1C are associated with X-linked mental retardation.
Description (Vector)
KDM5C is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants.
Gene ID
8242
Gene Name (eCommerce)
lysine demethylase 5C
Gene Name (Vector)
lysine demethylase 5C
Gene Symbol
KDM5C
HGNC ID
HGNC:11114
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4680
ORF Size (bp)
4680 bp
Protein Name (eCommerce)
Lysine-specific demethylase 5C
RefSeq ID
NM_004187
RefSeq Synonyms
NM_004187, NM_001282622, NM_001146702, BC054499,
Research Areas
Cancer,Chromatin Remodeling,Histone Modification,Neurobiology,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cancer,cell_biology,transcription_translation,genetics,neurobiology,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
JARID1C is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. Mutations in JARID1C are associated with X-linked mental retardation.
UniGene ID
Hs.631768
UniProt ID (eCommerce)
P41229

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.