human IYD Adenovirus
This is an Adenovirus expressing Human IYD.
ADV-212566
Ad-h-IYD
Ready-to-use Adenovirus expressing Human IYD (iodotyrosine deiodinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C6orf71; DEHAL1; IYD-1; TDH4
Description (Vector)
IYD encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants.
Gene ID
389434
Gene Name (Vector)
iodotyrosine deiodinase
Gene Symbol
IYD
HGNC ID
HGNC:21071
ORF Size (aa)
870
ORF Size (bp)
870 bp
RefSeq ID
NM_203395
RefSeq Synonyms
NM_203395, NM_001318495, NM_001164695, NM_001164694, BC056253,
Species
human
UniGene ID
Hs.310225
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.