human IRGM Adenovirus

Name 
Ad-h-IRGM
Cat No 
ADV-212416
Availability
4-5 weeks

This is an Adenovirus expressing Human IRGM.

ADV-212416
Ad-h-IRGM

Ready-to-use Adenovirus expressing Human IRGM (immunity related GTPase M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IFI1; IRGM1; LRG-47; LRG47
Description (Vector)
IRGM encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.
Gene ID
345611
Gene Name (Vector)
immunity related GTPase M
Gene Symbol
IRGM
HGNC ID
HGNC:29597
ORF Size (aa)
537
RefSeq ID
NM_001145805
RefSeq Synonyms
NM_001346557, NM_001145805, BC128168, BC128167,
Species
human
UniGene ID
Hs.652148

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.