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human IL15RA Adenovirus

Name 
Ad-h-IL15RA
Cat No 
ADV-212052
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IL15RA.

ADV-212052
Ad-h-IL15RA

Ready-to-use Adenovirus expressing Human IL15RA (interleukin 15 receptor subunit alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD215
Description (Vector)
IL15RA encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Gene ID
3601
Gene Name (Vector)
interleukin 15 receptor subunit alpha
Gene Symbol
IL15RA
HGNC ID
HGNC:5978
ORF Size (aa)
696
ORF Size (bp)
696 bp
RefSeq ID
NM_002189
RefSeq Synonyms
NM_172200, NM_002189, NM_001256765, NM_001243539, BC121141, BC121140, BC107777, BC074726,
Species
human
UniGene ID
Hs.524117

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.