human IL12RB1 Adenovirus
This is an Adenovirus expressing Human CWF19L2.
ADV-212036
Ad-h-IL12RB1
Ready-to-use Adenovirus expressing Human IL12RB1 (interleukin 12 receptor subunit beta 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD212; IL-12R-BETA1; IL12RB; IMD30
Description (Vector)
IL12RB1 is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Gene ID
3594
Gene Name (Vector)
interleukin 12 receptor subunit beta 1
Gene Symbol
IL12RB1
HGNC ID
HGNC:5971
ORF Size (aa)
1989
ORF Size (bp)
1989 bp
RefSeq ID
NM_005535
RefSeq Synonyms
NM_153701, NM_005535, NM_001290024, NM_001290023, BC137406, BC137404, BC029121,
Species
human
UniGene ID
Hs.567294
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.