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human IKBKAP Adenovirus

Name 
Ad-h-IKBKAP
Cat No 
ADV-212007
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IKBKAP.

ADV-212007
Ad-h-IKBKAP

Ready-to-use Adenovirus expressing Human IKBKAP (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DYS; elongator acetyltransferase complex subunit 1; elongator complex protein 1; ELP1; FD; IKAP; ikappaB kinase complex-associated protein; IKBKAP; IKI3; IKK complex-associated protein; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein; p150; TOT1
Description (eCommerce)
IKAP (IkappaB kinase complex-associated protein) is also known as ELP1 (elongator complex protein 1. IKAP functions as a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia [taken from NCBI Entrez Gene (Gene ID: 8518)].
Description (Vector)
IKBKAP is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia.
Gene ID
8518
Gene Name (eCommerce)
elongator complex protein 1
Gene Name (Vector)
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
Gene Symbol
IKBKAP
HGNC ID
HGNC:5959
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3999
ORF Size (bp)
3999 bp
Protein Name (eCommerce)
Elongator complex protein 1
RefSeq ID
NM_003640
RefSeq Synonyms
NM_003640, NM_001330749, NM_001318360, BC033094,
Research Areas
Cell Biology,Immunology,Interleukin Signaling,Kinase/Phosphatase,Neurobiology,Neurodegeneration,Neurodevelopment,Phosphatase,Signal Transduction,TNF Signaling,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
IKAP (IkappaB kinase complex-associated protein) is also known as ELP1 (elongator complex protein 1. IKAP functions as a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia [taken from NCBI Entrez Gene (Gene ID: 8518)].
UniGene ID
Hs.494738
UniProt ID (eCommerce)
O95163

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.