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human IGF2BP2 Adenovirus

Name 
Ad-h-IGF2BP2
Cat No 
ADV-211920
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IGF2BP2.

ADV-211920
Ad-h-IGF2BP2

Ready-to-use Adenovirus expressing Human IGF2BP2 (insulin like growth factor 2 mRNA binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Hepatocellular carcinoma autoantigen p62; IGF2 mRNA-binding protein 2; IGF-II mRNA-binding protein 2; IMP2; IMP-2; insulin-like growth factor 2 mRNA-binding protein 2; VICKZ family member 2; VICKZ2
Description (eCommerce)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific and may regulate translation of target mRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y6M1].
Description (Vector)
IGF2BP2 encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
10644
Gene Name (eCommerce)
insulin like growth factor 2 mRNA binding protein 2
Gene Name (Vector)
insulin like growth factor 2 mRNA binding protein 2
Gene Symbol
IGF2BP2
HGNC ID
HGNC:28867
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1797
ORF Size (bp)
1797 bp
Protein Name (eCommerce)
Insulin-like growth factor 2 mRNA-binding protein 2
RefSeq ID
NM_006548
RefSeq Synonyms
NM_006548, NM_001291875, NM_001291874, NM_001291873, NM_001291872, NM_001291869, NM_001007225, BC021290,
Research Areas
Cytoskeleton,Gene Expression,mRNA Binding,mRNA transport,RNA Binding,RNA Transport,Translational Control
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific and may regulate translation of target mRNAs [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9Y6M1].
UniGene ID
Hs.35354
UniProt ID (eCommerce)
Q9Y6M1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.