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human IARS2 Adenovirus

Name 
Ad-h-IARS2
Cat No 
ADV-211739
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IARS2.

ADV-211739
Ad-h-IARS2

Ready-to-use Adenovirus expressing Human IARS2 (isoleucyl-tRNA synthetase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAGSSS; ILERS; isoleucine tRNA ligase 2, mitochondrial; isoleucine--tRNA ligase, mitochondrial; isoleucine-tRNA synthetase 2, mitochondrial; Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, mitochondrial; mitochondrial isoleucine tRNA synthetase
Description (eCommerce)
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. IARS2 is the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family [taken from NCBI Entrez Gene (Gene ID: 55699)].
Gene ID
55699
Gene Name (eCommerce)
isoleucyl-tRNA synthetase 2, mitochondrial
Gene Name (Vector)
isoleucyl-tRNA synthetase 2, mitochondrial
Gene Symbol
IARS2
HGNC ID
HGNC:29685
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3039
ORF Size (bp)
3039 bp
Protein Name (eCommerce)
Isoleucine--tRNA ligase, mitochondrial
RefSeq ID
NM_018060
RefSeq Synonyms
NM_018060, BC137438, BC010218,
Research Areas
Gene Expression,Mitochondrion,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. IARS2 is the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family [taken from NCBI Entrez Gene (Gene ID: 55699)].
UniGene ID
Hs.262823
UniProt ID (eCommerce)
Q9NSE4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.