human HLA-G Adenovirus

Name 
Ad-h-HLA-G
Cat No 
ADV-211238
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human HLA-G.

ADV-211238
Ad-h-HLA-G

Ready-to-use Adenovirus expressing Human HLA-G (major histocompatibility complex, class I, G). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MHC-G
Description (Vector)
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
Gene ID
3135
Gene Name (Vector)
major histocompatibility complex, class I, G
Gene Symbol
HLA-G
HGNC ID
HGNC:4964
ORF Size (aa)
1017
ORF Size (bp)
1017 bp
RefSeq ID
NM_002127
RefSeq Synonyms
NM_002127, BC021708,
Species
human
UniGene ID
Hs.512152

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.