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human HIST1H3A Adenovirus

Name 
Ad-h-HIST1H3A
Cat No 
ADV-211117
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human HIST1H3A.

ADV-211117
Ad-h-HIST1H3A

Ready-to-use Adenovirus expressing Human HIST1H3A (histone cluster 1 H3 family member a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
H3 histone family, member A; H3/A; H3FA; histone 1, H3a; histone cluster 1, H3a; histone H3.1; histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l
Description (eCommerce)
Histone H3 is one of four histone proteins that assemble into an octamer to form the nucleosome core and serve to spool and compact DNA into chromatin. Histones are subject to a complex set of post-translational modifications (acetylation, methylation, phosphorylation, ubiquitination, sumoylation, citrullination, and ADP ribosylation) that are important to the regulation of gene transcription, DNA replication, and DNA repair.
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Gene ID
8350
Gene Name (eCommerce)
histone cluster 1 H3 family member a
Gene Name (Vector)
histone cluster 1 H3 family member a
Gene Symbol
HIST1H3A
HGNC ID
HGNC:4766
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
411
Protein Name (eCommerce)
Histone H3.1
RefSeq ID
NM_003529
RefSeq Synonyms
NM_003529, BC069303, BC067491, BC067490, BC066247, BC066246, BC066245,
Research Areas
Cancer,Cell Cycle,Chromatin Remodeling,Epigenetic Regulation of Gene Expression,Gene Expression,Histone Modification,Meiosis,Phospho-specific,Transcriptional Misregulation in Cancer
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,developmental_biology,genetics,transcription_translation
Species
human
Target Sentence
Histone H3 is one of four histone proteins that assemble into an octamer to form the nucleosome core and serve to spool and compact DNA into chromatin. Histones are subject to a complex set of post-translational modifications (acetylation, methylation, phosphorylation, ubiquitination, sumoylation, citrullination, and ADP ribosylation) that are important to the regulation of gene transcription, DNA replication, and DNA repair.
UniGene ID
Hs.546315
UniProt ID (eCommerce)
P68431

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.